KMID : 0869220140180020081
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Journal of Korean Geriatric Psychiatry 2014 Volume.18 No. 2 p.81 ~ p.85
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Relationship between Premorbid Personality and Behavioral and Psychological Symptoms in Dementia in Korean Patients with Alzheimer¡¯s Disease
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Gim Min-Sook
Choi Young-Min Lee Dong-Woo
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Abstract
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Objective£º We performed a cross-sectional study to examine the relationship between premorbid personality and behavioral and psychological symptoms in dementia (BPSD) in Korean patients with Alzheimer¡¯s disease (AD).
Methods£ºWe assessed 103 patients diagnosed with AD for the presence of BPSD over the disease course by using the caregiver-rated Korean version of the Neuropsychiatric Inventory (K-NPI) and for the premorbid personality by using a retrospective version of the NEO-Five Factor Inventory questionnaire completed by informants.
Results£ºPremorbid neuroticism was significantly correlated with delusion, agitation, anxiety, disinhibition, total K-NPI score (p£¼0.05), and sleep disturbances (p£¼0.01). Lower premorbid conscientiousness was significantly correlated with symptoms of hallucinations and sleep disturbances in AD patients (p£¼0.05). However, premorbid neuroticism and low premorbid conscientiousness did not act as independent predictors for ¡°psychosis, hyperactivity,¡± or ¡°moods, apathy, frontal¡± factors of BPSD.
Conclusion£ºPremorbid personality was associated with the K-NPI score, but was not observed to be potential predictors of BPSD.
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KEYWORD
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Alzheimer¡¯s disease, Behavioral and psychological symptoms in dementia, Premorbid personality
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